Science Signaling, Sep 2023
Transcriptomics-inferred dynamics of SARS-CoV-2 interactions with host epithelial cells
mBio, Aug 2023
Stanifer, M; Karst, S; Boulant, S
Regionalization of the antiviral response in the gastrointestinal tract to provide spatially controlled host/pathogen interactions
PLoS Comput Biol, Aug 2023
Benjamin Raach, Nils Bundgaard, Marika J. Haase, Joern Starruss, Rocio Sotillo, Megan L. Stanifer, Frederik Graw
Influence of cell type specific infectivity and tissue composition on SARS-CoV-2 infection dynamics within human airway epithelium
STAR Protocols, Dec 2022
Elena Garreta, Daniel Moya-Rull, Megan L. Stanifer, Vanessa Monteil, Patricia Prado, Andrés Marco, Carolina Tarantino, Maria Gallo, Gustav Jonsson, Astrid Hagelkruys, Ali Mirazimi, Steeve Boulant, Josef M Penninger, Nuria Montserrat
Protocol for SARS-CoV-2 infection of kidney organoids derived from human pluripotent stem cells
Journal of Virology, Sep 2022
Patricio Doldan, Jin Dai, Camila Metz-Zumaran, John T. Patton, Megan L. Stanifer, Steeve Boulant
Type III and Not Type I Interferons Efficiently Prevent the Spread of Rotavirus in Human Intestinal Epithelial Cells
Communication Biology, Aug 2022
Pasquale Laise , Megan L Stanifer , Gideon Bosker , Xiaoyun Sun , Sergio Triana , Patricio Doldan, Federico La Manna , Marta De Menna , Ronald B Realubit , Sergey Pampou , Charles Karan, Theodore Alexandrov , Marianna Kruithof-de Julio , Andrea Califano , Steeve Boulant , Mariano J Alvarez
A model for network-based identification and pharmacological targeting of aberrant, replication-permissive transcriptional programs induced by viral infection
Nature Genetics, Aug 2022
A Rouf Banday # , Megan L Stanifer # , Oscar Florez-Vargas # , Olusegun O Onabajo , Brenen W Papenberg , Muhammad A Zahoor , Lisa Mirabello , Timothy J Ring , Chia-Han Lee , Paul S Albert , Evangelos Andreakos , Evgeny Arons, Greg Barsh , Leslie G Biesecker , David L Boyle , Mark S Brahier, Andrea Burnett-Hartman, Mary Carrington, Euijin Chang, Pyoeng Gyun Choe, Rex L Chisholm, Leandro M Colli, Clifton L Dalgard, Carolynn M Dude, Jeff Edberg, Nathan Erdmann, Heather S Feigelson, Benedito A Fonseca, Gary S Firestein, Adam J Gehring, Cuncai Guo, Michelle Ho , Steven Holland , Amy A Hutchinson, Hogune Im, Les'Shon Irby, Michael G Ison, Naima T Joseph, Hong Bin Kim, Robert J Kreitman, Bruce R Korf, Steven M Lipkin, Siham M Mahgoub, Iman Mohammed, Guilherme L Paschoalini, Jennifer A Pacheco, Michael J Peluso, Daniel J Rader , David T Redden , Marylyn D Ritchie, Brooke Rosenblum, M Elizabeth Ross, Hanaisa P Sant Anna, Sharon A Savage, Sudha Sharma, Eleni Siouti, Alicia K Smith, Vasiliki Triantafyllia, Joselin M Vargas, Jose D Vargas, Anurag Verma, Vibha Vij , Duane R Wesemann, Meredith Yeager, Xu Yu, Yu Zhang, Steeve Boulant, Stephen J Chanock, Jordan J Feld , Ludmila Prokunina-Olsson
Genetic regulation of OAS1 nonsense-mediated decay underlies association with COVID-19 hospitalization in patients of European and African ancestries
Cell Death Disease, Aug 2022
Rebekka Karlowitz, Megan L Stanifer, Jens Roedig, Geoffroy Andrieux, Denisa Bojkova, Marco Bechtel, Sonja Smith, Lisa Kowald, Ralf Schubert, Melanie Boerries, Jindrich Cinatl Jr, Steeve Boulant, Sjoerd J L van Wijk
USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING
Cell Metab, May 2022
Garreta Elena, Prado Patricia, Stanifer Megan L, Monteil Vanessa, Marco Andrés, Ullate-Agote Asier, Moya-Rull Daniel, Vilas-Zornoza Amaia, Tarantino Carolina, Romero Juan Pablo, Jonsson Gustav, Oria Roger, Leopoldi Alexandra, Hagelkruys Astrid, Gallo Maria, González Federico, Domingo-Pedrol Pere, Gavaldà Aleix, Del Pozo Carmen Hurtado, Hasan Ali Omar, Ventura-Aguiar Pedro, Campistol Josep María, Prosper Felipe, Mirazimi Ali, Boulant Steeve, Penninger Josef M, Montserrat Nuria,
A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells.
Cell, May 2022
Alphonse Noémie, Wanford Joseph J, Voak Andrew A, Gay Jack, Venkhaya Shayla, Burroughs Owen, Mathew Sanjana, Lee Truelian, Evans Sasha L, Zhao Weiting, Frowde Kyle, Alrehaili Abrar, Dickenson Ruth E, Munk Mads, Panina Svetlana, Mahmood Ishraque F, Llorian Miriam, Stanifer Megan L, Boulant Steeve, Berchtold Martin W, Bergeron Julien R C, Wack Andreas, Lesser Cammie F, Odendall Charlotte,
A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling.