HIGHLIGHTED PUBLICATIONS

LATEST PUBLICATIONS

Communication Biology, Aug 2022

Pasquale Laise , Megan L Stanifer , Gideon Bosker , Xiaoyun Sun , Sergio Triana , Patricio Doldan, Federico La Manna , Marta De Menna , Ronald B Realubit , Sergey Pampou , Charles Karan, Theodore Alexandrov , Marianna Kruithof-de Julio , Andrea Califano , Steeve Boulant , Mariano J Alvarez 

A model for network-based identification and pharmacological targeting of aberrant, replication-permissive transcriptional programs induced by viral infection

Nature Genetics, Aug 2022

A Rouf Banday # , Megan L Stanifer # , Oscar Florez-Vargas # , Olusegun O Onabajo , Brenen W Papenberg , Muhammad A Zahoor , Lisa Mirabello , Timothy J Ring , Chia-Han Lee , Paul S Albert , Evangelos Andreakos , Evgeny Arons, Greg Barsh , Leslie G Biesecker , David L Boyle , Mark S Brahier, Andrea Burnett-Hartman, Mary Carrington, Euijin Chang, Pyoeng Gyun Choe, Rex L Chisholm, Leandro M Colli, Clifton L Dalgard, Carolynn M Dude, Jeff Edberg, Nathan Erdmann, Heather S Feigelson, Benedito A Fonseca, Gary S Firestein, Adam J Gehring, Cuncai Guo, Michelle Ho , Steven Holland , Amy A Hutchinson, Hogune Im, Les'Shon Irby, Michael G Ison, Naima T Joseph, Hong Bin Kim, Robert J Kreitman, Bruce R Korf, Steven M Lipkin, Siham M Mahgoub, Iman Mohammed, Guilherme L Paschoalini, Jennifer A Pacheco, Michael J Peluso, Daniel J Rader , David T Redden , Marylyn D Ritchie, Brooke Rosenblum, M Elizabeth Ross, Hanaisa P Sant Anna, Sharon A Savage, Sudha Sharma, Eleni Siouti, Alicia K Smith, Vasiliki Triantafyllia, Joselin M Vargas, Jose D Vargas, Anurag Verma, Vibha Vij , Duane R Wesemann, Meredith Yeager, Xu Yu, Yu Zhang, Steeve Boulant, Stephen J Chanock, Jordan J Feld , Ludmila Prokunina-Olsson

Genetic regulation of OAS1 nonsense-mediated decay underlies association with COVID-19 hospitalization in patients of European and African ancestries

Cell Metab, May 2022

Garreta Elena, Prado Patricia, Stanifer Megan L, Monteil Vanessa, Marco Andrés, Ullate-Agote Asier, Moya-Rull Daniel, Vilas-Zornoza Amaia, Tarantino Carolina, Romero Juan Pablo, Jonsson Gustav, Oria Roger, Leopoldi Alexandra, Hagelkruys Astrid, Gallo Maria, González Federico, Domingo-Pedrol Pere, Gavaldà Aleix, Del Pozo Carmen Hurtado, Hasan Ali Omar, Ventura-Aguiar Pedro, Campistol Josep María, Prosper Felipe, Mirazimi Ali, Boulant Steeve, Penninger Josef M, Montserrat Nuria,

A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells.

Cell, May 2022

Alphonse Noémie, Wanford Joseph J, Voak Andrew A, Gay Jack, Venkhaya Shayla, Burroughs Owen, Mathew Sanjana, Lee Truelian, Evans Sasha L, Zhao Weiting, Frowde Kyle, Alrehaili Abrar, Dickenson Ruth E, Munk Mads, Panina Svetlana, Mahmood Ishraque F, Llorian Miriam, Stanifer Megan L, Boulant Steeve, Berchtold Martin W, Bergeron Julien R C, Wack Andreas, Lesser Cammie F, Odendall Charlotte,

A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling.

Nat Commun, May 2022

Petitjean Simon J L, Chen Wenzhang, Koehler Melanie, Jimmidi Ravikumar, Yang Jinsung, Mohammed Danahe, Juniku Blinera, Stanifer Megan L, Boulant Steeve, Vincent Stéphane P, Alsteens David,

Multivalent 9-O-Acetylated-sialic acid glycoclusters as potent inhibitors for SARS-CoV-2 infection.

NPJ Syst Biol Appl, May 2022

Poletti Martina, Treveil Agatha, Csabai Luca, Gul Leila, Modos Dezso, Madgwick Matthew, Olbei Marton, Bohar Balazs, Valdeolivas Alberto, Turei Denes, Verstockt Bram, Triana Sergio, Alexandrov Theodore, Saez-Rodriguez Julio, Stanifer Megan L, Boulant Steeve, Korcsmaros Tamas,

Mapping the epithelial-immune cell interactome upon infection in the gut and the upper airways.

J Virol, Mar 2022

Metz-Zumaran Camila, Kee Carmon, Doldan Patricio, Guo Cuncai, Stanifer Megan L, Boulant Steeve,

Increased Sensitivity of SARS-CoV-2 to Type III Interferon in Human Intestinal Epithelial Cells.

Cancer Sci, Mar 2022

He Liping, Boulant Steeve, Stanifer Megan, Guo Cuncai, Nießen Anna, Chen Mingyi, Felix Klaus, Bergmann Frank, Strobel Oliver, Schimmack Simon,

The link between menin and pleiotrophin in the tumor biology of pancreatic neuroendocrine neoplasms.

mBio, Mar 2022

Shytaj Iart Luca, Fares Mohamed, Gallucci Lara, Lucic Bojana, Tolba Mahmoud M, Zimmermann Liv, Adler Julia M, Xing Na, Bushe Judith, Gruber Achim D, Ambiel Ina, Taha Ayoub Ahmed, Cortese Mirko, Neufeldt Christopher J, Stolp Bettina, Sobhy Mohamed Hossam, Fathy Moustafa, Zhao Min, Laketa Vibor, Diaz Ricardo Sobhie, Sutton Richard E, Chlanda Petr, Boulant Steeve, Bartenschlager Ralf, Stanifer Megan L, Fackler Oliver T, Trimpert Jakob, Savarino Andrea, Lusic Marina,

The FDA-Approved Drug Cobicistat Synergizes with Remdesivir To Inhibit SARS-CoV-2 Replication and Decreases Viral Titers and Disease Progression in Syrian Hamsters.

Mol Ther, Jan 2022

Becker Jonas, Stanifer Megan Lynn, Leist Sarah Rebecca, Stolp Bettina, Maiakovska Olena, West Ande, Wiedtke Ellen, Börner Kathleen, Ghanem Ali, Ambiel Ina, Tse Longping Victor, Fackler Oliver Till, Baric Ralph Steven, Boulant Steeve, Grimm Dirk,

Ex vivo and in vivo suppression of SARS-CoV-2 with combinatorial AAV/RNAi expression vectors.